Solicin film-coated tablets 5 mg No. 30

Solicin is a medicine for the symptomatic treatment of urge incontinence and/or frequent urination, as well as the urge to urinate, typical of patients with overactive bladder syndrome.

Warehouse

Contraindication

The drug is contraindicated in patients with hypersensitivity to the active substance or to any of the excipients of the drug.

Patients with urinary retention.

With severe gastrointestinal diseases (including toxic megacolon).

With myasthenia gravis or angle-closure glaucoma and patients at risk of developing these conditions.

During hemodialysis.

Method of application

Adults, including the elderly: The recommended dose is 5 mg of the drug once a day. If necessary, the dose can be increased to 10 mg once a day.

Patients with renal impairment: No dose adjustment is required for patients with mild to moderate renal impairment (creatinine clearance > 30 ml/min).

In patients with severe renal impairment (creatinine clearance ≤ 30 ml/min), solifenacin should be administered with caution and not more than 5 mg once daily.

Patients with hepatic impairment: No dose adjustment is required for patients with mild hepatic impairment. Patients with moderate hepatic impairment (Child-Pugh score 7 to 9) should use the drug with caution and not exceed a dosage of 5 mg once daily.

Application features

Before starting treatment with solifenacin, the possibility of other causes of frequent urination (heart failure or kidney disease) should be established. If a urinary tract infection is detected, appropriate antibacterial therapy should be initiated.

Pregnant women

There are no clinical data on women who became pregnant while taking solifenacin. Animal studies do not indicate direct adverse effects on fertility, embryonal/fetal development or parturition. The potential risk is unknown. Caution should be exercised when prescribing this drug to pregnant women.

Children

The safety and effectiveness of solifenacin in children have not been studied, so the drug should not be used in children.

Drivers

Since solifenacin, like other anticholinergic drugs, can cause blurred vision, as well as (rarely) drowsiness and fatigue, taking the drug may adversely affect the ability to drive and use machines.

Overdose

Overdose of solifenacin succinate can lead to severe anticholinergic effects. The highest dose of solifenacin succinate accidentally taken by one patient was 280 mg over 5 hours, which resulted in altered mental status but did not require hospitalization.

Side effects

Infections and infestations: urinary tract infections, cystitis.

Immune system: anaphylactic reaction.

Metabolic and trophic disorders: decreased appetite, hyperkalemia.

Psyche: hallucinations, confusion, delusions.

Nervous system: drowsiness, taste disturbance, dizziness, headache.

Storage conditions

Store in the original packaging at a temperature not exceeding 25°C.

Keep out of reach of children.