Instructions for Solvit Vitamin D3 4000 capsules No. 30
Composition
1 capsule contains: active ingredient: vitamin D3 (cholecalciferol) - 100 mcg (μg) / (4000 IU/IU); excipients: filler: inulin (fiber), anti-caking agent: magnesium stearate, capsule shell: gelatin.
Dietary supplement. Non-GMO.
Properties
Vitamin D3 (cholecalciferol) is a vital fat-soluble vitamin that helps maintain healthy immune function, strengthen the musculoskeletal system, increase the body's energy potential, support normal nervous system function, and improve reproductive function in both women and men.
Biological role of vitamin D3
participates in the regulation of phosphorus-calcium metabolism: helps absorb calcium in the intestines, maintains the necessary levels of calcium and phosphorus in the blood, activates bone tissue metabolism. Helps ensure the strength of bones and teeth, reduces the risk of rickets and osteomalacia;
helps maintain muscle strength and neuromuscular conduction, thereby reducing the risk of falls and fractures;
normalizes the functions of the immune system, has a positive effect on both innate and acquired immunity. Triggers the synthesis of the body's own antimicrobial peptides. Helps reduce the risk of developing colds. Has a regulatory effect on the growth, development and renewal of cells. Lack of vitamin D in the body leads to a weakening of the body's immune defense;
helps reduce fatigue and increase the body's tone, regulates the cells' own energy potential. As a result of the influence of vitamin D in the mitochondria of cells, the production of ATP increases, which is the body's own universal source of energy for all biochemical processes occurring in the body;
positively affects the activity of the nervous system, including the psycho-emotional sphere and cognitive functions (mood, memory, attention, performance, general tone of the body), as it participates in the production of neurotransmitters, biologically active substances that transmit nerve impulses between nerve cells. It is necessary for the conversion of tryptophan (an amino acid that enters the body with food) into serotonin, a neurotransmitter that is of great importance for normal cognitive function and the psycho-emotional state of a person;
stimulates the synthesis of female and male sex hormones: estrogen, progesterone, testosterone.
It has a positive effect on reproductive function, both in women and men. In women with sufficient levels of vitamin D, fertilization of eggs occurs more often. The absence of vitamin D deficiency allows to improve the results of IVF (in vitro fertilization). This effect is due to the effect of vitamin D on the endometrium. The use of vitamin D allows to increase the thickness of the endometrium in women with polycystic ovary syndrome;
Vitamin D deficiency is a risk factor for the development of insulin resistance, impaired glucose tolerance. Vitamin D can stimulate the secretion of insulin by pancreatic beta cells, and also indirectly activates beta-cell calcium-dependent endopeptidase, which converts proinsulin into active insulin.
Vitamin D can affect tissue sensitivity to insulin by stimulating the expression of insulin receptors in cells. Vitamin D has a positive effect on lipid metabolism, the inner layer and muscle wall of blood vessels, as well as on blood clotting processes;
helps reduce the level of total cholesterol, triglycerides and low-density lipids in the blood;
According to the European Food Safety Authority (EFSA), the maximum permissible daily intake of vitamin D is: for adults and children aged 11 years and older - 100 mcg (4000 IU). The appointment of a daily dose higher than 4000 IU is recommended after analysis of the concentration of 25 (OH) D in the blood (Tables 4-5).
Laboratory evaluation of vitamin D deficiency
| Vitamin D deficiency level | Serum 25(OH)D concentration ng/mL (nmol/L) |
| Severe deficiency | < 10 ng/mL (< 25 nmol/L) |
| Deficit | < 20 ng/mL (< 50 nmol/L) |
| Insufficiency | 21 30 ng/mL (51 75 nmol/L) |
| Adequate level | >30 ng/mL (>75 nmol/L) |
| Levels with probable manifestation of vitamin D toxicity | >150 ng/mL (>375 nmol/L) |
Algorithm for determining the optimal dose of vitamin D
| Expected level (ng/ml) | Recommended daily intake of vitamin D3 (IU) |
| 10 | 20 | 30 | 40 | 50 | 60 |
| 15 | 2000 | 4000 | 6000 | 10000 | 10000 |
| 20 | 1000 | 3000 | 6000 | 9000 | 10000 |
| 25 | 2000 | 5000 | 8000 | 10000 | |
| 30 | 1000 | 4000 | 7000 | 10000 | |
| 35 | 1000 | 5000 | 9000 | | |
| 40 | 3000 | 6000 | | | |
Recommendations for use
As a dietary supplement to the diet as an additional source of vitamin D3, in case of vitamin D deficiency, as well as in conditions requiring its additional use. It is advisable to use for people who spend little time in the sun, as well as in conditions requiring additional use of vitamin D (for fractures, osteoporosis, calcium absorption disorders, joint and thyroid diseases, metabolic syndrome, reproductive function disorders in men and women).
Method of application
Adults and children aged 11 years and older should take 1 capsule once a day during meals; drink plenty of room temperature liquid.
Reservation
Before use, it is recommended to consult a doctor. During pregnancy and lactation, vitamin D3 should enter the body in the required amount. Vitamin D3 during pregnancy and lactation should be taken only as needed and in a daily dose clearly defined by a doctor.
Contraindication
Individual sensitivity to the components, hypercalcemia, hypercalciuria, vitamin D hypervitaminosis, nephrolithiasis. Not a medicinal product.
Release form
30 capsules with a content weight of 500 mg (mg) ±10%.
Expiration date
24 months from the date of manufacture.
Storage conditions
Store in original packaging, at a temperature of 4°C to 25°C, in a dry place, out of reach of children.
Producer
SOLEPHARM Ltd, Latvia, Alkšnju 4, Jaunmārupe, Marupe region, LV-2166.
Name, location and telephone number of the enterprise that performs functions of accepting claims from consumers: LLC "BAZKID PHARM GROUP", Ukraine, 01021, Kyiv, 28/2 Hrushevskoho St., n/p. 43.
