Torasemide tablets 10mg No. 30




Torasemide acts as a saluretic, its action is associated with inhibition of renal absorption of sodium and chloride ions in the ascending limb of the loop of Henle. It is indicated for the treatment and prevention of recurrence of edema and/or effusions caused by heart failure.
Composition
Active ingredient: torasemide.
1 tablet contains 10 mg of torasemide.
Excipients: lactose monohydrate, corn starch, colloidal anhydrous silicon dioxide, magnesium stearate.
Contraindication
Hypersensitivity to the active substance, sulfonylurea drugs and to any of the excipients of the medicinal product. Renal failure with anuria. Hepatic coma or precoma. Arterial hypotension. Hypovolemia. Hyponatremia. Hypokalemia.Method of application
Treatment should be initiated with a daily dose of 5 mg torasemide, which is equivalent to ½ a tablet of Torasemide. This dose is usually considered a maintenance dose.
Application features
Pregnant women
Torasemide is not recommended for use during pregnancy, as well as in women of reproductive age who are not using contraception.
Children
The safety and efficacy of the drug Torasemide in children and adolescents under 18 years of age have not been established; therefore, it should not be used in patients in this age category.
Drivers
Even when used properly, torasemide may adversely affect the reaction rate when driving or operating machinery. This primarily applies to the beginning of treatment, the period of increasing the dose of the drug, changing the drug, prescribing concomitant therapy and drinking alcohol. Therefore, special care should be taken when driving or operating machinery when using torasemide.
Overdose
Overdose may cause excessive diuresis, including the risk of excessive loss of water and electrolytes, drowsiness, confusional state, symptomatic hypotension, circulatory collapse and digestive disorders.
Adverse reactions
General manifestations. Often: headache, dizziness, increased fatigue, general weakness (especially at the beginning of treatment). Sometimes: dry mouth, unpleasant sensations in the extremities (paresthesia). Very rarely: visual disturbances, ringing in the ears, hearing loss.
Interaction
Torasemide, especially in high doses, may enhance the ototoxic and nephrotoxic effects of aminoglycoside antibiotics, such as kanamycin, gentamicin, tobramycin and cytostatics - active platinum derivatives, as well as the nephrotoxic effects of cephalosporins. With the simultaneous use of torasemide and lithium preparations, an increase in the concentration of lithium in the blood plasma is possible, which may lead to increased exposure to lithium and the manifestation of adverse reactions.
Storage conditions
Store in the original packaging at a temperature not exceeding 25 °C.
Shelf life - 2.5 years.
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