Tranexamic acid solution for injection 50 mg/ml ampoule 5ml No. 10

Tranexamic acid injection solution is indicated for use in patients with hemophilia for short-term use (for 2-8 days) to reduce or prevent bleeding, as well as reduce the need for replacement therapy during and after tooth extraction.

Composition

The active substance is tranexamic acid (1 ml of solution contains tranexamic acid in terms of 100% anhydrous substance - 50 mg).

The excipient is water for injection.

Contraindication

Method of application

Immediately before tooth extraction, patients with hemophilia should be given 10 mg/kg of tranexamic acid intravenously along with replacement therapy. Intravenous treatment with this drug at a dose of 10 mg/kg of body weight 3-4 times a day can be used for 2-8 days after tooth extraction.

Application features

Pregnant women

Tranexamic acid crosses the placenta and is found in cord blood at concentrations approximately equal to those in the mother. This drug should be used during pregnancy only if clearly needed.

Tranexamic acid is present in human milk at concentrations approximately 1/100 of the corresponding serum level. Caution should be exercised when administering tranexamic acid to women who are breastfeeding.

Children

The use of this medication in children is limited and is prescribed mainly in connection with tooth extraction.

Drivers

Tranexamic acid may cause dizziness and may therefore affect the ability to drive or use machines.

Overdose

In case of overdose, gastrointestinal symptoms may occur, for example: nausea, vomiting, diarrhea; hypotensive symptoms, for example, orthostatic symptoms; thromboembolic symptoms, for example: arterial, venous, embolic; neurological symptoms, for example: visual disturbances, seizures, headache, changes in mental status; myoclonus; skin rash.

Side effects

Gastrointestinal disturbances (nausea, vomiting, diarrhea) may occur, but they disappear when the dose is reduced. Allergic dermatitis, dizziness and hypotension have been observed occasionally. Hypotension has been noted in cases where intravenous injection has been performed too rapidly. To avoid this reaction, the solution should be administered at a rate of no more than 1 ml/minute.

Storage conditions

Store in the original packaging at a temperature not exceeding 25 °C, out of the reach of children.

Shelf life - 2 years.