Trazograf 76% solution for injection 76% ampoule 20 ml No. 5

Pharmacological properties

Radiocontrast iodine-containing diagnostic agent. Increases image contrast due to the absorption of X-rays by iodine, which is part of the drug.

Reversibly binds to blood plasma proteins (mainly with the albumin fraction). Poorly absorbed in the digestive tract and rapidly excreted from the body when administered intravenously. Penetrates the blood-brain barrier. Excreted from the body almost unchanged in the urine and in small quantities - with feces.

Indication

Trazograph 76% is used for intravenous and retrograde urography, coronary angiography, as well as for obtaining images of contrast-enhanced body cavities (computed tomography, hysterosalpingography).

Trazograph 60% is used for intravenous and retrograde urography, cerebral angiography, angiography of vessels of the thoracic and abdominal cavities, extremities, phlebography, as well as for computed tomography.

Application

2 days before the examination, the patient should avoid eating foods that can cause flatulence (legumes, salads, coarse black or freshly baked bread, milk and vegetables). The patient should not eat after 6:00 p.m. the day before, as well as on the day of the examination. A cleansing enema is performed in the evening, if necessary, a laxative is prescribed 2 days before the examination. The patient should fast on the day of the examination. Gases should be removed from the stomach and intestines in bedridden patients.

For IV urography in adult patients, the dose is 1-1.5 ml/kg body weight, for coronary angiography - an average of 30-60 ml for Trazograf 76% and 20-60 ml for Trazograf 60%. The recommended average duration of administration is 2-3 minutes. The first X-ray examination is performed 3-5 minutes, and the second - 10-12 minutes after infusion.

For infants and young children, the dose is 2-3 ml/kg body weight. The average dose is 8 ml; the maximum dose should not, as a rule, exceed 20 ml. The first examination is performed 2-3 minutes after the infusion.

In patients with impaired renal function, the study is performed after 30-40 minutes or later.

Contraindication

Absolute - severe forms of hyperthyroidism, decompensated heart failure, intolerance to iodine-containing drugs, severe renal and hepatic failure, active tuberculosis and pulmonary emphysema, myocardial disease, severe hypertension, shock and collapse, acute phlebitis (for phlebography).

Relative - atherosclerosis of cerebral vessels, decompensated diabetes mellitus, increased blood clotting, mild forms of nodular goiter, plasmacytoma, pregnancy, severe general condition of the patient.

Side effects

Nausea, vomiting, dizziness, skin flushing, cyanosis, feeling of heat and pain during injection of the drug. Allergic reactions are possible, including urticaria, angioedema, bronchospasm or anaphylactic shock.

Special instructions

Examination with Trazograf during pregnancy is carried out only in case of extreme necessity.

Trazograph 60% is not used for selective coronary angiography and myelography.

Storage conditions

At room temperature in a place protected from light and X-rays.