Pharmacological properties
Pharmacodynamics. The drug contains a combination of vitamins with calcium and phosphorus. Vitamins are substances that participate in the regulation of many biochemical processes in the body. The effect of vitamins and minerals in the body is largely physiological, rather than pharmacodynamic.
The B group of vitamins (B 1, B 2, B 6, B 12, pantothenic acid, nicotinamide and folic acid) participates in the metabolism of carbohydrates, proteins and fats, and also plays an important role in the functioning of the nervous system.
Folic acid is necessary for the formation, regeneration, and normal functioning of blood cells.
Vitamin A is necessary for the development of epithelial cells and the synthesis of visual pigment.
Vitamin D regulates calcium absorption and enables proper mineralization of bones and teeth.
Vitamin C promotes iron absorption and participates in many redox processes in the body.
Minerals are components of connective tissue and act as activators and components of enzymes.
Calcium and phosphorus play an important role in the mineralization of bones and teeth.
Calcium ions activate many enzymes, participate in the regulation of heart muscle tone, in the regulation of the transmission of nerve impulses, and regulate the permeability of cell membranes.
Pharmacokinetics. Water-soluble vitamins (B vitamins, vitamin C and biotin) are well absorbed in amounts corresponding to the daily requirement. Excess amounts are excreted in the urine and in some cases also in the feces. These vitamins are stored in the body in limited quantities, so they must be regularly supplied with food to maintain the necessary concentration in the tissues.
In the presence of fat, orally administered fat-soluble vitamins A and D are well absorbed in the small intestine. When used in large amounts, these vitamins are stored and deposited in the liver, making them more toxic than water-soluble vitamins.
Indication
The medicine is intended for children with:
reduced appetite; physical and mental overload in schoolchildren; developmental delay; as an adjunct to antibiotic treatment; seasonal deficiency of fruits and vegetables in the diet.
Application
Inside after meals.
For the prevention of hypovitaminosis: children aged 4-6 years - 1 tablet 1-2 times a day; children aged 7-14 years - 1 tablet 2-3 times a day.
For the treatment of hypovitaminosis: children aged 4-6 years - 1 tablet 4 times a day; children aged 7-14 years - 1 tablet 5 times a day.
For reduced appetite, the drug Univit is recommended to be used for 2 months, for other indications - as needed, depending on the duration and frequency of symptoms after consulting a doctor.
Contraindication
Hypersensitivity to the active substances or any of the excipients of the drug; hypervitaminosis A and D; nephrolithiasis; gout; hyperuricemia; erythremia; erythrocytosis; thrombophlebitis; thromboembolism; disorders of iron and copper metabolism; hypercalcemia; hypercalciuria; thyrotoxicosis; chronic glomerulonephritis; chronic heart failure; history of sarcoidosis; gastric and duodenal ulcers (due to the possibility of increased acidity of gastric juice); tuberculosis.
Side effects
On the part of the immune system: possible hypersensitivity reactions to the components of the drug, including anaphylactic shock, bronchospasm, angioedema.
Metabolism and digestion: hypercalcemia.
From the nervous system: headache, dizziness, drowsiness.
On the part of the organ of vision: visual impairment.
Gastrointestinal tract: dyspepsia, nausea, vomiting, belching, stomach pain, constipation, diarrhea, increased secretion of gastric juice.
Skin and subcutaneous tissue disorders: rash, urticaria, itching, redness.
From the kidneys and urinary tract: urine discoloration, hypercalciuria.
General disorders: hyperthermia, irritability, hyperhidrosis.
During prolonged use in high doses, the following adverse reactions may occur.
Metabolism and digestion: hyperuricemia, impaired glucose tolerance, hyperglycemia.
Nervous system: paresthesia.
Cardiovascular system: arrhythmias.
Gastrointestinal disorders: gastrointestinal disorders.
Skin and subcutaneous tissue disorders: hair loss, seborrhea.
Renal and urinary disorders: renal failure.
Laboratory indicators: temporary increase in AST, LF, LDH levels.
If any adverse reactions occur, discontinue use of the drug and consult a doctor.
Special instructions
The drug is not recommended for use in children under 4 years of age. Before using it together with other vitamin, vitamin-mineral and/or mineral drugs, you should consult a doctor.
The drug is prescribed with caution to patients with liver diseases, acute nephritis, cardiac decompensation, cholelithiasis, chronic pancreatitis, allergic diseases, idiosyncrasies, and neoplasms.
The urine may turn yellow due to the presence of riboflavin in the preparation. This effect is safe.
Since the drug contains sorbitol, patients with rare hereditary fructose intolerance should not take this drug.
The drug contains aspartame, which is transformed into phenylalanine in the body, so it should not be used by patients with phenylketonuria.
The drug contains sugar, which should be taken into account by patients with diabetes.
Use during pregnancy and breastfeeding. The drug is used in children.
Children. The drug is used in children over 4 years of age.
Ability to influence the reaction rate when driving or operating other mechanisms. There are no reports of the drug's effect on the ability to drive or operate other mechanical devices.
Interactions
Due to the possibility of developing hypervitaminosis A, simultaneous use of the drug with other drugs containing vitamin A or with oral retinoids is not recommended.
High doses of vitamin C should not be used when treating with sulfonamides to avoid crystalluria. Pyridoxine reduces the effectiveness of levodopa if the patient is taking levodopa alone.
Riboflavin interferes with the absorption and reduces the effectiveness of antibiotics. Therefore, it should be taken at least 3 hours before taking the antibiotic.
Overdose
When taking the recommended doses, overdose is unlikely. Symptoms. Long-term use (more than 1 month) of the drug in very high doses can cause hypervitaminosis of vitamins A and D. However, the possibility of overdose when using the drug is unlikely.
Treatment is symptomatic.
Storage conditions
In the original packaging at a temperature not exceeding 25 °C.
Translation of the instructions can be
