Ureotope ointment for external use 12% tube 50 g

Pharmacological properties

The use of highly concentrated urea preparations in the treatment of dermatological diseases is based, first of all, on the keratoplastic effect of urea. In addition, cutaneous applications of concentrated urea preparations increase the fluid content in the stratum corneum of the human epidermis. Urea is a natural moisturizer that improves water binding in the upper layers of the skin and reduces its loss by the epidermis. The effectiveness of such agents in the treatment of ichthyosis, psoriasis and a positive effect in patients with dry and sensitive skin have been proven. Urea has a low molecular weight, due to which it is quickly absorbed. Along with its hydrating properties, urea has a keratolytic effect, which is why the skin softens quickly and hard scales exfoliate.

Excipients included in the ointment retain the active substance (urea) at the site of application, thereby preventing its absorption into the systemic bloodstream. The absorbed urea is excreted through urine and in small quantities through sweat.

Indication

It is used to treat neurodermatitis (including in the elderly), as well as as an adjuvant in the treatment of ichthyosis.

Application

The ointment should be applied 1-2 times a day, until symptoms are relieved, on thoroughly cleansed dry skin, rubbing in intensively. An occlusive dressing is used as prescribed by a doctor. There is no clinical information on the use of Ureotope ointment for more than 3 weeks.

Contraindication

Hypersensitivity to propylene glycol or any component of the drug. Do not use for the treatment of acute skin inflammation.

Side effects

According to the data obtained, the occurrence of side effects is classified as follows:

Allergic reactions to the substances contained in this medicine may occur infrequently, including skin irritation such as burning, redness, itching or peeling.

If any of the listed side effects significantly worsens your condition or if you experience a side effect not listed in the instructions, you should inform your doctor.

Special instructions

Avoid contact of the ointment with mucous membranes, do not apply around the eyes, as this may lead to irritation. Do not use to treat acute inflammation of damaged skin. If a large amount of the drug is accidentally swallowed and symptoms of intoxication occur, consult a doctor.

Use during pregnancy and breastfeeding. There is no data on the use of Uretop during pregnancy or breastfeeding, therefore, taking the drug during this period is not recommended.

Children. There are no data on the use of Uretop ointment in children, therefore the drug is not used in pediatric practice.

The ability to influence the reaction speed when driving vehicles or working with other mechanisms. Does not affect.

Interactions

Increased skin absorption of other topically applied agents (especially corticosteroids) is possible. Concomitant use of other drugs containing urea or its derivatives is not recommended.

Overdose

There are no data on overdose cases.

Storage conditions

At a temperature not exceeding 25 °C. after first opening the tube, the shelf life is 6 months.