Instructions Validol sublingual tablets 0.06 g blister No. 50
Composition
active ingredient: 1 tablet contains a solution of menthol in menthyl ester of isovaleric acid (natural menthol - mint extract - 4.9%) - 0.06 g (60 mg);
excipients: granulated sugar (powder), calcium stearate.
Dosage form
Sublingual tablets.
Main physical and chemical properties: flat-cylindrical tablets with a bevel and a score, white or yellowish-white in color, with a characteristic menthol odor. Gray inclusions and a coating of powdered sugar are allowed on the surface of the tablets.
Pharmacotherapeutic group
Cardiological drugs. ATX code C01E X.
Pharmacological properties
Pharmacodynamics.
The drug has a calming effect on the central nervous system, and also causes a moderate reflex vasodilator (coronarolytic) effect by reflex irritation of sensitive nerve ("cold") receptors of the oral mucosa. Stimulation of receptors is accompanied by induction of the release of endorphins, enkephalins, dynorphins and other peptides, histamine, kinins, which play an important role in reducing pain sensitivity, normalizing vascular permeability and regulating other important mechanisms of the functioning of the cardiovascular and nervous systems.
Pharmacokinetics.
When used sublingually, Validol® is absorbed from the oral mucosa. The therapeutic effect occurs after approximately 5 minutes.
After absorption, it is biotransformed in the liver and excreted in the urine in the form of glucuronides.
Indication
- Mild angina attacks;
- sea and air sickness;
- hysteria;
- neurosis;
- headache associated with taking nitrates.
Contraindication
Hypersensitivity to the components of the drug. Severe arterial hypotension, acute myocardial infarction.
Interaction with other medicinal products and other types of interactions
Reduces the severity of headaches caused by taking nitrates. Potentiation of sedative and antihypertensive effects is possible with simultaneous use with other psychotropic and antihypertensive drugs, opioid analgesics, anesthetics and alcohol.
Application features
In cases where pain in the heart area does not go away after taking the drug, it is necessary to consult a doctor to rule out acute coronary syndrome.
The medicine contains sugar, which should be taken into account by patients with diabetes.
Use during pregnancy or breastfeeding
The use of the drug during pregnancy or breastfeeding is possible if, in the opinion of the doctor, the expected positive effect for the mother outweighs the potential risk to the fetus/child.
Ability to influence reaction speed when driving vehicles or other mechanisms
Caution is required in the first hours after taking the drug when driving vehicles or performing work that requires increased attention, as dizziness, drowsiness, and decreased psychomotor speed are possible.
Method of administration and doses
Keep the tablets in your mouth (under the tongue) until completely dissolved.
A single dose for adults is 1–2 tablets; daily dose is 2–4 tablets.
If necessary, the daily dose can be increased. The maximum daily dose is 600 mg.
The duration of treatment is up to 7 days.
Children.
There is no experience in using the drug to treat children.
Overdose
Symptoms: headache, nausea, agitation, cardiac dysfunction, decreased blood pressure, central nervous system depression.
Treatment: drug withdrawal and symptomatic treatment.
Side effects
With prolonged use, mild nausea, abdominal discomfort, tearing, dizziness, short-term arterial hypotension, drowsiness may occasionally occur, which quickly resolve on their own.
Allergic reactions may develop, including angioedema, urticaria, rashes, and itching.
Expiration date
2 years.
Do not use the drug after the expiration date indicated on the package.
Storage conditions
Store in original packaging at a temperature not exceeding 15 °C.
Keep out of reach of children.
Packaging
10 tablets in a blister. 1 or 5 blisters in a pack.
10 tablets in a blister without packaging.
Vacation category
Without a prescription.
Producer
JSC "Farmak".
Address
Ukraine, 04080, Kyiv, Kyrylivska St., 74.
