Virax tablets 250 mg No. 21

Virax tablets are indicated for:

Composition

Active ingredient: famciclovir;

1 tablet contains famciclovir 125 mg or 250 mg or 500 mg;

Excipients: corn starch, sodium lauryl sulfate, microcrystalline cellulose, croscarmellose sodium, colloidal silicon dioxide, stearic acid, Opadry white OY-S-28924 (hypromellose (5 CP), titanium dioxide (E171), hypromellose (15 HC), macrogol 4000, macrogol 6000).

Contraindication

Hypersensitivity to famciclovir or other components of the drug, as well as sensitivity to penciclovir.

Method of application

Since the systemic bioavailability of penciclovir was not altered when famciclovir was taken with food, famciclovir can be administered without regard to meals.

For the treatment of shingles - 500 mg 3 times a day for 7 days. For the treatment of shingles with eye complications - 500 mg 3 times a day for 7 days. Treatment gives better results if it is started immediately after the appearance of the rash.

Application features

Pregnant women

By doctor's prescription.

Children

Contraindicated.

Drivers

With caution.

Overdose

Data on overdose with famciclovir are limited. Reports of accidental acute overdoses (10.5 g) are limited. Long-term use (10 g per day for 2 years) of famciclovir did not cause complications. In case of overdose, supportive therapy should be used. Isolated cases of acute renal failure have been described in patients with a history of kidney disease, for whom the dose of Virax was reduced accordingly. The concentration of the drug is reduced by approximately 75% during 4-hour hemodialysis.

Side effects

In general, adverse reactions reported in clinical trials in immunocompromised patients were similar to those reported in immunocompetent patients. Nausea, vomiting and changes in liver function tests were reported more frequently, especially at higher doses.

Interaction

No clinically significant effect on the pharmacokinetics of zidovudine, its metabolites - zidovudine glucuronide or emtricitabine - was observed after a single dose of 500 mg famciclovir when co-administered with zidovudine or emtricitabine.

Storage conditions

Store below 30°C in the original packaging to protect from moisture.

Keep out of reach of children.

Shelf life - 2 years.