Zocardis plus 30/12.5 film-coated tablets blister No. 28

Zocardis Plus tablets are indicated for essential hypertension of mild to moderate severity.

Composition

Active ingredients: zofenopril calcium, hydrochlorothiazide;

1 film-coated tablet contains zofenopril calcium 30 mg, equivalent to zofenopril 28.7 mg, and hydrochlorothiazide 12.5 mg;

Excipients: microcrystalline cellulose, lactose, corn starch, hypromellose, colloidal silicon dioxide, magnesium stearate, titanium dioxide (E 171), polyethylene glycol 400, polyethylene glycol 6000, red iron oxide (E 172).

Contraindication

Method of application

Zocardis® Plus 30/12.5 should be taken once a day, regardless of meals.

For easier swallowing, the tablet can be divided into two halves and swallowed alternately at the appointed time.

Application features

Pregnant women

Contraindicated.

Children

The use of the drug in children is not recommended due to the lack of data on safety and efficacy.

Drivers

With caution.

Overdose

Symptoms of overdose include severe hypotension, shock, stupor, bradycardia, electrolyte disturbances, and renal failure.

Side effects

From the nervous system: dizziness, headache.

Respiratory, thoracic and mediastinal disorders: cough.

Gastrointestinal: nausea, vomiting.

Interaction

Concomitant use with sacubitril/valsartan therapy. Treatment with Zocardis® Plus 30/12.5 can be started no earlier than 36 hours after the last dose of sacubitril/valsartan.

The simultaneous use of Zocardis® Plus 30 / 12.5 and drugs containing aliskiren is contraindicated in patients with diabetes mellitus or impaired renal function (GFR <60 ml/min / 1.73 m 2).

Storage conditions

Store at a temperature not exceeding 30 °C.

Keep out of reach of children.

Shelf life - 3 years.